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Hair Loss Explained
In the vast majority of men who experience balding,
the cause is a condition referred to in the medical literature
as "Androgenetic Alopecia". This is a fancy term for the
kind of balding that we commonly call male pattern baldness. "Pattern"
baldness is simply what the name implies. It occurs in a pattern
and is usually not related to any disease process.
Norwood Classification of Male Pattern Hair
Loss
Andro refers to Androgens or male hormones.
Male hormones are normally present to a greater degree in men
and to a much lesser degree in women. The term genetic
refers to the genetic or inherited nature of balding. This is
how it works. Every hair follicle has a genetic program inherited
from both parents at conception (not the mother only) that controls
this type of hair loss. At some point in time, because of this
genetic program, certain follicles within the balding pattern
become sensitive or vulnerable to the follicle killing effects
of male hormone or "Androgen." Other follicles outside
the pattern with a different genetic program remain insensitive
or invulnerable to these effects.
So it's not the location of the follicle, but the
follicle itself, and more specifically the genetic program of
each follicle. These Androgen sensitive follicles then begin to
change; they become progressively smaller, called miniaturization
(see illustration below) and grow progressively shorter hair shafts
because of a shortened growth phase (see illustration below).
Miniaturization of The Hair Follicle

Please note, hair follicles exist in three phases
of growth:
1. A growth phase called the Anagen phase,
typically lasting three or four years, followed by
2. A short shriveling up phase called the
Catagen phase, followed by
3. A dormant or resting phase called the Telogen
phase, usually lasting three or four months.
Most of your follicles, approximately 90% to 95%
(most people start out with about 100,000 hair follicles), are
in the growth phase, growing approximately one half inch per month.
An average anagen or growth phase will last three
years or more. This will allow the hair shaft to grow about 18
to 24 inches before it sheds, or falls out. This happens when
the growing follicle changes phases (see illustration below).
This change in phase is why we normally shed 50 to 100 hairs per
day.

Some individuals actually have follicles with an
unusually long growth or anagen phase, permitting the hair shafts
to grow several feet in length before falling out. Remember that
cheerleader in high school who had hair down past her waist? She
obviously had follicles with a very long anagen phase. If however,
your growth phase is unusually short, the hair shaft won't achieve
much length. As mentioned, that's one of the things that happens
when the "Androgen sensitive" follicles within the pattern
are continually exposed to normally present male hormone or Androgen.
Let's recap and put it all together. Each hair follicle has a
genetic code determined at conception. This genetic code controls
"if" and "when" each follicle will become
vulnerable to the hair killing effects of normally present male
hormone or Androgen. When this happens, Androgen begins to slowly
kill the now vulnerable follicles by:
1. Causing Miniaturization.
2. Shortening the Anagen Phase (or growth phase).
As a result, the hair within the pattern becomes progressively
finer, shorter, and falls out more frequently.
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Perrault Medical Hair Restoration. All rights reserved.
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in Medical Hair Restoration and the Treatment of Hair Loss |